Which of the following is NOT a key handling requirement for hazardous drugs under USP <800>?

• A. Engineering controls
• B. PPE
• C. No training
• D. Proper packaging

Answer: (C)

Under USP <800>, protecting workers who handle hazardous drugs relies on three main safeguards: engineering controls to contain aerosols and spills, appropriate PPE to protect skin and eyes, and proper packaging to prevent leakage during storage and transport. In addition, every staff member must receive formal training before handling hazardous drugs, covering safe handling practices, spill response, decontamination, and waste management. Therefore, “No training” is not a valid requirement—training is required. The other elements—engineering controls, PPE, and proper packaging—are indeed required components of USP <800> compliance.